This study was designed to investigate the probable effect of Garden Cress seeds (GCs) on the bone of osteoporotic female rats. Thirty healthy adult female albino rats (weigh, 200±10g) were used in this study. The rats were haphazardly divided into two main groups. The first main group (6 rats) was fed on a basal diet as a control negative group. The second main group (24 rats) fed on a basal diet containing 100mg prednisone acetate as a source of glucocorticoid/kg diet for two weeks to induce osteoporosis. One group was selected as a positive control group, three groups were fed on prednisone acetate diets containing GCs powder at the level of 2.5, 5, and 7.5%.The biological results showed a significant improvement (P≤0.05) in values of Ca and P in serum and femur bone of osteoporotic rats fed on a basal diet containing different ratios of GCs. Bone mineral content and bone mineral density also increased as compared to the control positive group. Kidney and liver functions significantly (P≤0.05) improved compared to the positive control group. The histological examination of bone confirmed a gradual improvement in all treated groups. Peanut sweets were produced with proportions 2.5, 5, and 7.5% of GCs, sensory evaluation indicated that all peanut sweets samples have an acceptance greater than 75%. In conclusion, the current study indicates that GCs have improved osteoporosis biomarkers in rats and can be used up to 7.5% as a supplement in the diet of osteoporosis patients.
Arafa, R., & El-kholey, H. (2021). The Potential Effects of Garden Cress Seeds (Lepidium Sativum L.) on the Bone of Female Rats Suffering from Osteoporosis. مجلة البحوث في مجالات التربية النوعية, 7(37), 1399-1426. doi: 10.21608/jedu.2021.96960.1471
MLA
Rasha Arafa; Heba El-kholey. "The Potential Effects of Garden Cress Seeds (Lepidium Sativum L.) on the Bone of Female Rats Suffering from Osteoporosis". مجلة البحوث في مجالات التربية النوعية, 7, 37, 2021, 1399-1426. doi: 10.21608/jedu.2021.96960.1471
HARVARD
Arafa, R., El-kholey, H. (2021). 'The Potential Effects of Garden Cress Seeds (Lepidium Sativum L.) on the Bone of Female Rats Suffering from Osteoporosis', مجلة البحوث في مجالات التربية النوعية, 7(37), pp. 1399-1426. doi: 10.21608/jedu.2021.96960.1471
VANCOUVER
Arafa, R., El-kholey, H. The Potential Effects of Garden Cress Seeds (Lepidium Sativum L.) on the Bone of Female Rats Suffering from Osteoporosis. مجلة البحوث في مجالات التربية النوعية, 2021; 7(37): 1399-1426. doi: 10.21608/jedu.2021.96960.1471