Effect of Yogurt Supplemented with Date Fruit, Seeds and Leaves on Blood Sugar of Diabetic Rats

Author

Department of Home Economics, Faculty of Qualitative Education, Ain Shams University

Abstract

Abstract: Nowadays, tend to use synthetic drugs to lower serum glucose in diabetic patients is gradually decreased because of their related side effects, as well as a progression of drug resistance. In this regard, tend to use of medicinal plants has been doubled. Therefore, this work was conducted to investigate the effect of date fruit, leaves and seed at the level of 10% on diabetic rats. Thirty five adult male albino rat of Sprague Dawley strain, weighing (176.5±1.20 g) were divided in two main groups. The first main group (n=7) was kept as negative control group, the second main group (n=28) was injected interperitonial with Streptozotocin (STZ) to induce diabetes, then these rats were divided into four subgroups. Subgroup one was fed on the basal diet and served as a positive control group, subgroups from 2 to 3 were fed on basal diet and supplemented with yogurt and date fruit, seed, and leaves at the level of 10% respectively. At the end of the experimental period (8 weeks), rats were sacrificed and blood samples were collected to obtain serum. The results indicated that, STZ treated rats showed significant reduction (P<0.05) in serum insulin concentration and, increased glucose levels compared to normal rats. Supplementation with yogurt and date fruit, seed, or leaves in the diet caused significant (P<0.05) increase in the concentration of insulin while glucose level was significantly (P<0.05) decreased compared to the positive control one. It was also observed that, liver and kidney functions and lipid profile of the treated rats was improved compared to the positive control group. In conclusion, diet supplemented with yogurt and date fruit, seed, and leaves caused an improvement of the biochemical results from diabetes, therefore yogurt and date fruit, seed, or leaves could be used as a suitable supplementation therapy for diabetic patients.   

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