Effect of feeding some selected food processing by-products on blood oxidant and antioxidant status of obese rats

Zakria Mahran, Mohamed

doi:10.21608/jedu.2018.104979

Effect of feeding some selected food processing by-products on blood oxidant and antioxidant status of obese rats

Author

mohamed zakria mahran

Department of Nutrition and Food Sciences - Faculty of Home Economics - Menoufia University - Shebin El-Koum - Egypt

10.21608/jedu.2018.104979

Abstract

: The present study aims to investigate the effect of feeding some selected food processing by-products on blood oxidant and antioxidant status of obese rats. Forty two male rats, (weight 139±5.3g per each), were divided into two main groups, the first group (Group 1, 6 rats) still fed on basal diet and the other main group (36 rats) was feed with diet-induced obesity (DIO) for 8 weeks which classified into sex sub groups as follow: group (2), fed on DIO as a positive control; groups (3-7), fed on DIO containing 7.5 % tomato pomace powder (TPP), potato peel powder (PPP), cauliflower leaves powder (CLP), eggplant peel powder (EPP and their mixture, respectively. At the end of the experiment (8 weeks), rats of the obese group recorded body weight gain (BWG, 149.02%, as a percent of the baseline. Feeding of TPP, PPP, CLP, EPP and their mixture (Mix) induced significant decreasing on BWG of the obese rats which recorded 120.83, 138.32, 135.51, 127.65 and 119.02% as a percent of the baseline, respectively. Biochemical analysis data indicated that obesity induced a significant increased (p≤0.05) in plasma oxidants concentration (TBARS, 39.10%; NO2, 31.02% and NO2/NO3, 27.10%) and significant decreased (p≤0.05) in plasma non-enzymes antioxidant (GSH, -35.45% and GSSG, -18.07%), plasma antioxidant vitamins (vitamin A, -27.43%; vitamin C, -18.39% and vitamin E, -23.04%) as well as RBC's antioxidant enzymes (GSH-Px, -39.35%; GSH-Rd, -31.52%; CAT, -29.65% and SOD, -25.03%) as a percent of normal control group. Feeding on 7.5% of TPP, PPP, CLP, EPP and their mixture exhibited a significant improvement (p≤0.05) in all of these parameters by different rates. The higher amelioration effects were recorded for the mixture treatment followed by TPP, EPP, CLP and PPP, respectively. In conclusion, the present data support the benefits of dietary modification, including bioactive compounds in plant parts supplementation, in alleviating oxidative stress associated obesity.

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