Antioxidant Activity of Beetroot Powder on Alloxan Induced Diabetic Rats

Authors

1 Home economic faculty El monefia university

2 specific education alex university

Abstract

 iabetes mellitus (DM) is one of the most serious diseases that affect human health; DM is predicted to be the seventh leading cause of death by 2030 in the world. Diabetes particularly Type 2 is characterized by persistent production of reactive oxygen species (ROS) and generation of oxidative stress. Natural antioxidants have shown improving in treatment of diabetes. Therefore, this study was conducted to investigate the antioxidant activity of beetroot powder (BP) in different concentrations on alloxan - induced diabetic rats. Thirty adult male albino rats weighting (160±10) were divided into 5 equal groups of 6 animals each, one was kept as a control -Ve group, while the other 4 groups were treated with alloxan (150 mg/kg body weight) to induce diabetes mellitus. Group (2) were left as a control +Ve (diabetic rats) fed on normal diet at all experiment period (28 days), group 3,4 and 5 diabetic rats treated with 2%, 4% and 8% of beetroot powder, respectively. Liver enzymes activities, lipid profiles, antioxidant enzymes and glucose level in serum were examined. Significant increased in antioxidant enzymes activities of groups treated with beetroot powder in different concentrations. Treatment with BP with different concentration resulted in decreasing the rise of mean serum liver enzymes activities and prevented the rise of mean glucose concentrations in diabetic groups.  On conclusion, the present study demonstrated the daily consumption of beetroot powder with meals could be potentially useful in improving hyperglycemia and diabetic complications.

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