Study The Effect of Rice & Psyllium Husks and their Extracts on Diabetic Rats

Authors

1 Al-Azhar University, Faculty of Home Economics, Department of Nutrition and Food Sciences

2 Faculity of home economics nutrition and food scince department Al_Azhar University _ Tanta

3 Lecturer in Nutrition and Food ScienceDept., Faculty of Home Economics, Al Azhar University

Abstract

Diabetes is a metabolic disorder characterized by various physiological mechanisms that lead to elevated blood sugar levels. This study evaluated the effect of rice and psyllium husks and their extracts on diabetic rats. Thirty-six mature male rats were divided into two main groups as follow: Group (1): fed on basal diet only and kept as a negative control group (n =6). Group (2): (Diabetes mellitus group) thirty rats were be fasted overnight and then given a single intraperitoneal injections of 60mg/kg streptozotocin . After that, the rats which were divided into equal five groups (6 rats each) as following: Group (1): left as positive control and fed on basal diet only. Group (2): received psyllium husk extract at doses of 100mg per kg body weight. Group (3): received basal diet supplemented with 5% psyllium husk (50g/ kg diet). Group (3): received rice husk extract at doses of 100mg per kg body weight. Group (5): received basal diet supplemented with 5% rice husk (50g/ kg diet). The doses were given for 28 consecutive days. At the end of the experiment, feed intake (FI), body weight gain (BWG%) and feed efficiency ratio (FER) were calculated .Serum glucose ,lipid profile liver enzymes (AST, ALT, ALP) and kidney function were assessed. A histological examination of the pancreas, kidneys, and liver were performed. Results showed that these treatments improved blood sugar levels, blood lipids, kidney and liver function. Therefore, consuming psyllium and rice husks and their extracts may be beneficial for improving blood sugar.

Keywords

Main Subjects