The Potential Protective Effects Of Diet Fortified With Mung bean And ‎Soybean Against Oxidative Stress Caused By High Fat Diet In Rats

Document Type : Original Article

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Fayoum University

Abstract

This study was carried out to determine the potential ‎protective effects of diet fortified with Mung bean and ‎Soybean against what is caused by a high-fat diet in rats. Forty-‎eight mature male albino rats weighing (220 ± 5 g) were used in the study. The ‎rats were randomly separated into six groups rats were fed a ‎basic diet- normal diet (ND) , high-fat diet (HFD), HFD +10% mung bean ‎‎(HFDM‐10%) , HFD +10% soybean (HFDS‐10%), HFD +50% mung beans ‎‎(HFDM‐50%), and HFD +50% soybeans (HFDS‐50%).The lipid profile in the serum were evaluated. The hepatic changes and activities of ‎SOD, MDA, GSH-Px, CAT, and T- AOC were tested .Total phenols and scavenging activity were detected. The results ‎showed that diet fortified with 50% of mung bean and soybean can greatly ‎restore the levels of total cholesterol, low density lipoprotein cholesterol, and ‎high density lipoprotein cholesterol in serum. Liver staining showed that ‎‎(HFD) caused to liver lesions, whereas mung bean and soybean could ‎significantly improve these symptoms. The antioxidant defense system in ‎legume groups showed markedly improvement compared with the (HFD) ‎group. All these results showed that mung beans and soybean can be used as a ‎natural antioxidant.

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