Study of the Effect of Frankincense on the Hind Paw Edema of Rats

Document Type : Original Article

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Nutrition & Food Science Dept., Faculty of Home Economics, Menoufia Univ., Egypt

Abstract

Edema, also spelled oedema, dropsy, is the build-up of fluid in the body's tissue, most commonly, the legs or arms. This study aimed to evaluate the effect of frankincense in different concentrations on adult male albino rats on anti hind paw edema. Thirty white male albino rats were divided into 6 groups (5 rats each) weighing 220 ± 5g. The first and second groups fed on standard diet the third, fourth, fifth and sixth groups fed standard diet containing 5,10,15 and 20% frankincense powder respectively .After 28 days rats second to sixth groups were injected by 0.1 ml /kg formalin to cause hind paw edam, after 28 days from injection of formalin and ingesting diet supplemented with 5,10,15 and 20% frankincense the results recorded .The highest ESR reduction and hind paw edema weight levels recorded for group fed on frankincense powder (20%) while, the lowest value recorded for group fed on frankincense (5%) with significant difference. The highest reduction of cholesterol , triglycerides ,AST ,ALT, Urea, Creatinine and Uric acid levels recorded for on frankincense powder (20%) with significant difference .From the results, it could be recommended that (20%) leve of frankincense is effective in improving lipid metabolism and preventing ESR increise in hind paw edema.

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