Study the Potentials Antitoxicity Effects of Carthamus tinctorius extract on Rats Induced by Heterocyclic Compounds Containing Nitrogen

Zahran, Nasser

doi:10.21608/jedu.2021.85751.1424

Study the Potentials Antitoxicity Effects of Carthamus tinctorius extract on Rats Induced by Heterocyclic Compounds Containing Nitrogen

Author

Nasser Zahran

Menoufia University Hospitals

10.21608/jedu.2021.85751.1424

Abstract

The purpose of this paper was to investigate the study potentials antitoxicity effects of Carthamus tinctorius (CT) extract on some organs of rats induced by heterocyclic compounds containing nitrogen and spreading nutritional awareness of the benefits of medicinal plants and how to use them. The present study conducted to evaluate the effects of CT extract via determination of bioelements and antioxidant levels in brain and testes tissues of rats. Forty-two (42) Sprague-Dawley white male albino rats, each weighing 215±10g; rats were divided into 6 groups, every 7 rats in each group fed on a certain diet for 28 days. CT extract and vitamin C will be used at 100 mg/kg of rats' weight, while melamine will be used at 2%. Polyphenols are a large family of naturally occurring organic compounds and have gained a lot of importance because of their potential use as prophylactic and therapeutic agents in many diseases. We determined some significant changes about levels of bioelements in rats’ brain and testes tissues exposed to the CT extract. The results clarified that the groups fed on CT extract were the best compared to the other groups, especially the (-Ve). Based on current information, the pharmacological functions, including the antioxidant, anti-inflammatory, anti-diabetic, brain and testes protective effects of polyphenols, can be effectively exploited in the development of new drugs to treat various human brain and testes diseases.

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