Clinical Nutrition of CCl4 Induced Hepatointoxicated Male Albino Rats by Curry Leaves, Turmeric and Their Mix

Document Type : Original Article

Author

Department of Family Education Faculty of Education Umm AL-Qura University

Abstract

This investigation aimed to evaluate the effect of turmeric, curry leaves and mix diets on hepatointoxicated rats injected with CCl4. Thirty (30) adult male Sprague Dawley rats were divided into five groups. Group (1): Normal rats fed on basal diet as control negative (C-), Group (2): Control positive (C+) (untreated group). Group (3): Hepatointoxicated rats injected with CCl4 fed on basal diet and turmeric (4%).Group (4) Hepatointoxicated rats injected with CCl4 fed on basal diet and curry leaves (4%). Group (5): Hepatointoxicated rats injected with CCl4 fed mix diets (4%). At the end of experiment, after 28 days of feeding, all serum samples were analyzed for biochemical parameters. Injection with CCl4 caused significant decreases in BWG, FI, FER, TP, Alb, Glb, HDL & antioxidant enzymes with significant increases recorded also in organs weight, TC, TG, VLDL, LDL, U.A, creatinine, urea, GOT, GPT, ALP, glucose, total bilirubin, direct bilirubin (D.B) and indirect bilirubin (I.B). Rats treated with various (turmeric, curry) diets, showed the improvement in all previous parameters.

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