Effect of Soybean Flour, Coconut Oil and Magnesium on Rats Suffering from Non-Alcoholic Fatty Liver

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Fayoum University

Abstract

The current research was conducted to study the effect of low-fat soybean flour, virgin coconut oil, magnesium and all of them on rats suffering from non-alcoholic fatty liver disease (NAFLD), through some nutritional and biochemical parameters, in addition to estimating the chemical composition of soybean flour and the fatty acids composition of virgin coconut oil which used in this study. Sixty adult male albino rats of the (Sprague Dawley) strain were included in this study. The results indicated that treating NAFLD rats with low-fat soybean flour, coconut oil, and magnesium improved the nutritional and biochemical parameters by reducing (body weight gain %, liver weight%, glucose, leptin hormone, cholesterol, triglycerides, LDL-c, VLDL-c, AST, ALT, and ALP), and increasing HDL-c and antioxidant enzymes in the liver (GSH-Px, SOD, and CAT), significantly. The best results recorded for the NAFLD groups which treated with HFD containing low-fat soybean flour as the source of protein with replacing 20% coconut oil instead of 20% sheep tallow and supplemented with 1000 mg magnesium/ kg diet.

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