Immune boosting and Anti-oxidant activities of kiwifruit extract on hydrogen peroxide induced toxicity in mice

Fakher El Deen, Rania; Awad, Nanees

doi:10.21608/jedu.2021.56236.1180

Immune boosting and Anti-oxidant activities of kiwifruit extract on hydrogen peroxide induced toxicity in mice

Document Type : Original Article

Authors

Rania Fakher el deen ¹
Nanees Awad ²

¹ Home economics, faculty of specific education,Tanta university

² Home Economics Department, Faculty of Specific Education, Mansoura University, Egypt.

10.21608/jedu.2021.56236.1180

Abstract

Kiwi fruit is known as Chinese gooseberry and considered as natural dietary supplement with many health benefits. This study aims to assess the immune boosting and antioxidant effect of kiwi fruit (KWF) with three different forms in hydrogen peroxide (H2O2) induced toxicity in rats. Twenty-five rats, divided into five groups (5 rats for each); as normal control group (-ve), H2O2 (+ve) (100mg H2O2/kg bwt/day), treated groups were ((+ve) with oral KWF juice (100 mg /kg/bwt/day), ((+ve) with KWF powder (10g/kg diet/day), and ((+ve) with KWF mixture oral (100mg/kg bwt/day & powder10g /kg diet/day). At the end of the experiment, all rats were sacrificed and their serum was analyzed. The results showed that all groups treated by kiwi fruit significantly diminish the toxicity of H2O2 by decreasing MDA, AST, ALT, creatinine, urea and uric acid and increasing the levels of GSH, SOD, total antioxidants, blood parameters and nutritional parameters in serum of all groups which received kiwi fruit in comparison with H2O2 (+ve). In conclusion kiwi fruit juice and powder with different levels has some significant immune boosting and antioxidant effects.

Keywords