Contribution Role of Celery Seeds and Pomegranate Peel diets in Restoration the Normal, Biological, Biochemical & Histological Status of Hypercholesterolemic Rats

Document Type : Original Article

Author

makah

Abstract

This investigation aimed to evaluate the effect of celery seeds, pomegranate peel and mix diets of them on male hypercholesterolemic rats. Thirty (30) adult male Sprague Dawley rats were divided into five (5) groups. Group (1): Normal rats fed on basal diet as control negative (C-), Group (2): Control positive (C+) (untreated group). Group (3): Hypercholesterolemic rats fed on basal diet and celery seeds (5%). Group (4): Hypercholesterolemic rats fed on basal diet and pomegranate peel (5%). Group (5): Hypercholesterolemic rats fed on basal diet and mix diets (5%). At the end of experiment, after 28 days of feeding, all serum samples were analyzed for biochemical parameters. Hypercholesterolemic rats caused a significant decrease in BWG and HDL while a significant increase was recorded in serum TC, TG, VLDL, LDL, U.A, Creatinine, Urea, AST, ALT, ALP and Glucose. Hypercholesterolemic rats treated with various diets, showed the improvement in all previous parameters.

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