Study the Effects of Galangal and Phyllanthus Herbs on Hepatointoxicated White Rats Injected with Carbon Tetrachloride

Document Type : Original Article

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Nutrition and Food Science (Applied Nutrition), Department of Family Education, Unvirsity of Umm Al-Qura, Makka Al-Mukarama, Kingdom Saudi Arabia

Abstract

This investigation aimed to evaluate the effect ofgalangal, phyllanthus and mix diets onhepatointoxicated rats injected with CCl4. Thirty (30) adult male Sprague Dawley rats were divided into five groups. Group (1): Normal rats fed on basal diet as control negative (C-), Group (2): Control positive (C+) (untreated group). Group (3): Hepatointoxicated rats injected with CCl4 fed on basal diet and galangal(5%).Group (4) Hepatointoxicated rats injected with CCl4 fed on basal diet and phyllanthus (5%). Group(5): Hepatointoxicated rats injected with CCl4 fed mix diets (5%). At the end of experiment, after 28 days of feeding, all serum samples were analyzed forbiochemical parameters. Injected with CCl4 caused significant decreases in BWG, FI, TP, Alb, Glb, HDLand antioxidant enzymes while significant increasesrecorded in organs weight, TC, TG, VLDL, LDL, U.A, Creatinine, Urea, GOT, GPT, ALP, glucoseTotal bilirubin, Direct bilirubin (D.B) and Indirect bilirubin (I.B). Rats treated with various diets, showed the improvement in all previous parameters.

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