Chemical and Nutraceutical Studies of Obese Rats Using Rhubarb and Astragalus Herbs

Document Type : Original Article

Author

Faculty of Education, Department of Family Education., Unvirsity of Umm Al-Qura, Makka Al-Mukarama

Abstract

This investigation aimed to evaluate the effect of Rhubarb, Astragalus and Mixture of both on male obese rats. Thirty (30) adult male Sprague Dawley rats were divided into five groups. Group (1): Normal rats fed on basal diet as control negative (C-), Group (2): Control positive (C+) (untreated group). Group (3): Obese rats fed on basal diet and rhubarb (5%).Group (4): Obese rats fed on basal diet and astragalus (5%). Group (5): Obese rats fed on basal diet and mixture of both (5%). At the end of experiment, after 28 days of feeding, all serum samples were analyzed for biochemical parameters. Obese rats caused a significant decrease in the level of Hb, Ht, RBC, WBC, Neutrophils, Lymphocytes, Monocytes, Eosinphils and Basophils while a significant increase was recorded in TC, TG, VLDL, LDL, AI, U.A, Creatinine, Urea, GOT, GPT, ALP, Glucose and Plt. Obese rats treated with various diets, showed the improvement in all previous parameters.

Keywords

Main Subjects