Effect of pine fruits on some biological changes in hypercholesterolemia rats induced

Document Type : Original Article

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Faculty of Specific Education, Benha University

Abstract

This study aimed to determine chemical composition, antioxidant contents, fatty acids of pine nut fruits and also, the effect of pine powder with different ratio (3, 6 and 9%) on biochemical changes of hypercholesterolemic rats. Biological evaluation of growth performance, Lipid profile, serum protein, blood sugars, liver and kidney functions were also studied. The obtained results indicated that pine nut fruits are considered as a good source of oils, crude fibers, ash, protein, soluble carbohydrates, total energy polyphenols and flavonoids. Besides, it is a rich source of unsaturated fatty acids mainly, linoleic acid (C18:2) which represent more than half amount of total fatty acids. Biological evaluations showed that pine nut was significantly decreased (P ≤ 0.05) of body weight, total lipids, triglycerides, LDL, HDL, VLDL cholesterol of serum hypercholesterolemic rats as compared with positive group of rats Also, it caused significant decrease (P ≤ 0.05) in liver enzyme (AST, ALT and ALP) and kidney parameters (urea, uric acid and creatinine, i.e. improved liver and kidney functions as compared with positive control group. Meanwhile, both total protein and albumin were increased.

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